Recombinant human soluble thrombomodulin is associated with attenuation of sepsis-induced renal impairment by inhibition of extracellular histone release

Multiple organ dysfunction induced by sepsis often involves kidney injury. Extracellular histones released in response to damage-associated molecular patterns are known to facilitate sepsis-induced organ dysfunction. Recombinant human soluble thrombomodulin (rhTM) and its lectin-like domain (D1) exe...

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Detalles Bibliográficos
Autores principales: Akatsuka, Masayuki, Masuda, Yoshiki, Tatsumi, Hiroomi, Yamakage, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977725/
https://www.ncbi.nlm.nih.gov/pubmed/31971961
http://dx.doi.org/10.1371/journal.pone.0228093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977725/
https://www.ncbi.nlm.nih.gov/pubmed/31971961
http://dx.doi.org/10.1371/journal.pone.0228093

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