HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells

OBJECTIVES: Aging HIV-infected antiretroviral-treatment (ART)-controlled patients often present cardiovascular and metabolic comorbidities. Thus, it is mandatory that life-long used ART has no cardiometabolic toxicity. Protease inhibitors have been associated with cardiometabolic risk, integrase-str...

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Detalles Bibliográficos
Autores principales: Auclair, Martine, Guénantin, Anne-Claire, Fellahi, Soraya, Garcia, Marie, Capeau, Jacqueline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977740/
https://www.ncbi.nlm.nih.gov/pubmed/31971958
http://dx.doi.org/10.1371/journal.pone.0226924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977740/
https://www.ncbi.nlm.nih.gov/pubmed/31971958
http://dx.doi.org/10.1371/journal.pone.0226924

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