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HIV antiretroviral drugs, dolutegravir, maraviroc and ritonavir-boosted atazanavir use different pathways to affect inflammation, senescence and insulin sensitivity in human coronary endothelial cells
OBJECTIVES: Aging HIV-infected antiretroviral-treatment (ART)-controlled patients often present cardiovascular and metabolic comorbidities. Thus, it is mandatory that life-long used ART has no cardiometabolic toxicity. Protease inhibitors have been associated with cardiometabolic risk, integrase-str...
Autores principales: | Auclair, Martine, Guénantin, Anne-Claire, Fellahi, Soraya, Garcia, Marie, Capeau, Jacqueline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977740/ https://www.ncbi.nlm.nih.gov/pubmed/31971958 http://dx.doi.org/10.1371/journal.pone.0226924 |
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