ALU transposition induces familial hypertrophic cardiomyopathy

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is characterized by left ventricular hypertrophy (LVH) in the absence of predisposing cardiovascular conditions. Pathogenic variants in at least 16 cardiac sarcomeric genes have been implicated in HCM, most of which act in a dominant‐negative fashion. Ho...

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Detalles Bibliográficos
Autores principales: Nfonsam, Landry, Huang, Lijia, Carson, Nancy, McGowan‐Jordan, Jean, Beaulieu Bergeron, Melanie, Goobie, Sharan, Conacher, Susan, McCarty, David, Benson, Lee, Hewson, Stacy, Zahavich, Laura, Sinclair‐Bourque, Elizabeth, Smith, Amanda, Potter, Ryan, Ghani, Mahdi, Bronicki, Lucas, Jarinova, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978237/
https://www.ncbi.nlm.nih.gov/pubmed/31568709
http://dx.doi.org/10.1002/mgg3.951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978237/
https://www.ncbi.nlm.nih.gov/pubmed/31568709
http://dx.doi.org/10.1002/mgg3.951

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