Ganaxolone enhances microglial clearance activity and promotes remyelination in focal demyelination in the corpus callosum of ovariectomized rats

AIM: Experimental studies have shown that the progesterone metabolite, allopregnanolone, is endowed with promyelinating effects. The mechanisms underlying these promyelinating effects are not well understood. Therefore, we explored the impact of allopregnanolone's synthetic analogue, ganaxolone...

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Detalles Bibliográficos
Autores principales: Mouihate, Abdeslam, Kalakh, Samah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978248/
https://www.ncbi.nlm.nih.gov/pubmed/31332963
http://dx.doi.org/10.1111/cns.13195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978248/
https://www.ncbi.nlm.nih.gov/pubmed/31332963
http://dx.doi.org/10.1111/cns.13195

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