Construction and evaluation of an efficient C‐Jun siRNA to downregulate matrix metalloproteinase in human keratinocytes and fibroblasts under UV exposure

BACKGROUND: C‐Jun and EGFR have not been explored as targets via the mechanism of RNA silencing. Hence, this study designed an efficient C‐Jun‐h‐825 small interfering RNA (siRNA) and investigated its effect on matrix metalloproteinase (MMP) and collagen expression in human keratinocytes exposed to U...

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Detalles Bibliográficos
Autores principales: Xiao, Hong, Yang, Ruinian, Yang, Fang, Zhao, Yanan, Liu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978249/
https://www.ncbi.nlm.nih.gov/pubmed/31729200
http://dx.doi.org/10.1002/mgg3.1047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978249/
https://www.ncbi.nlm.nih.gov/pubmed/31729200
http://dx.doi.org/10.1002/mgg3.1047

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