Corticosterone induces neurotoxicity in PC12 cells via disrupting autophagy flux mediated by AMPK/mTOR signaling

AIMS: Our previous study indicated that chronic stress caused autophagy impairment and subsequent neuron apoptosis in hippocampus. However, the mechanism underlying the stress‐induced damage to neurons is unclear. In present work, we investigated whether stress‐level glucocorticoids (GCs) GCs promot...

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Detalles Bibliográficos
Autores principales: Ma, Run‐Dong, Zhou, Gui‐Juan, Qu, Miao, Yi, Ji‐Hong, Tang, Ya‐Ling, Yang, Xiang‐Yi, Nie, Ya‐Xiong, Gu, Hong‐Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978254/
https://www.ncbi.nlm.nih.gov/pubmed/31423743
http://dx.doi.org/10.1111/cns.13212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978254/
https://www.ncbi.nlm.nih.gov/pubmed/31423743
http://dx.doi.org/10.1111/cns.13212

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