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Regulation of hippocampal neuronal apoptosis and autophagy in mice with sepsis‐associated encephalopathy by immunity‐related GTPase M1
AIMS: Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Our goal was to investigate the role of immunity‐related GTPase M1 (IRGM1) in SAE and its underlying mechanism. METHODS: A mouse sepsis model was established by cecal ligation and perforation. SAE was diagnosed b...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978258/ https://www.ncbi.nlm.nih.gov/pubmed/31612615 http://dx.doi.org/10.1111/cns.13229 |