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Combined with anti‐Nogo‐A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques

In spinal cord injured adult mammals, neutralizing the neurite growth inhibitor Nogo‐A with antibodies promotes axonal regeneration and functional recovery, although axonal regeneration is limited in length. Neurotrophic factors such as BDNF stimulate neurite outgrowth and protect axotomized neurons...

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Detalles Bibliográficos
Autores principales: Beaud, Marie‐Laure, Rouiller, Eric M., Bloch, Jocelyne, Mir, Anis, Schwab, Martin E., Schmidlin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978268/
https://www.ncbi.nlm.nih.gov/pubmed/31418518
http://dx.doi.org/10.1111/cns.13213