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Combined with anti‐Nogo‐A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques
In spinal cord injured adult mammals, neutralizing the neurite growth inhibitor Nogo‐A with antibodies promotes axonal regeneration and functional recovery, although axonal regeneration is limited in length. Neurotrophic factors such as BDNF stimulate neurite outgrowth and protect axotomized neurons...
Autores principales: | Beaud, Marie‐Laure, Rouiller, Eric M., Bloch, Jocelyne, Mir, Anis, Schwab, Martin E., Schmidlin, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978268/ https://www.ncbi.nlm.nih.gov/pubmed/31418518 http://dx.doi.org/10.1111/cns.13213 |
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