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Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli

Pathogenic Escherichia coli can cause fatal diarrheal diseases in both animals and humans. However, no antibiotics or antimicrobial peptides (AMPs) can adequately kill resistant bacteria and clear bacterial endotoxin, lipopolysaccharide (LPS) which leads to inflammation and sepsis. Here, the LPS-tar...

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Detalles Bibliográficos
Autores principales: Wang, Zhenlong, Liu, Xuehui, Da Teng, Mao, Ruoyu, Hao, Ya, Yang, Na, Wang, Xiao, Li, Zhanzhan, Wang, Xiumin, Wang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978316/
https://www.ncbi.nlm.nih.gov/pubmed/31974490
http://dx.doi.org/10.1038/s42003-020-0761-3