Flagellin adjuvanted F1/V subunit plague vaccine induces T cell and functional antibody responses with unique gene signatures

Yersinia pestis, the cause of plague, could be weaponized. Unfortunately, development of new vaccines is limited by lack of correlates of protection. We used pre- and post-vaccination sera and peripheral blood mononuclear cells from a flagellin adjuvanted F1/V vaccine trial to evaluate for protectiv...

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Detalles Bibliográficos
Autores principales: Hamzabegovic, Fahreta, Goll, Johannes B., Hooper, William F., Frey, Sharon, Gelber, Casey E., Abate, Getahun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978331/
https://www.ncbi.nlm.nih.gov/pubmed/31993217
http://dx.doi.org/10.1038/s41541-020-0156-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978331/
https://www.ncbi.nlm.nih.gov/pubmed/31993217
http://dx.doi.org/10.1038/s41541-020-0156-y

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