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Flagellin adjuvanted F1/V subunit plague vaccine induces T cell and functional antibody responses with unique gene signatures
Yersinia pestis, the cause of plague, could be weaponized. Unfortunately, development of new vaccines is limited by lack of correlates of protection. We used pre- and post-vaccination sera and peripheral blood mononuclear cells from a flagellin adjuvanted F1/V vaccine trial to evaluate for protectiv...
Autores principales: | Hamzabegovic, Fahreta, Goll, Johannes B., Hooper, William F., Frey, Sharon, Gelber, Casey E., Abate, Getahun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978331/ https://www.ncbi.nlm.nih.gov/pubmed/31993217 http://dx.doi.org/10.1038/s41541-020-0156-y |
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