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p53 functional states are associated with distinct aldehyde dehydrogenase transcriptomic signatures

p53 and aldehyde dehydrogenase (ALDH) have been implicated in key tumorigenesis processes including cancer initiating cell (CIC) maintenance; however, the relationship between these two mediators remains poorly defined. In this study, ALDH isoform expression diversity was revealed in CICs with dispa...

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Detalles Bibliográficos
Autores principales: Gui, Shanying, Xie, Xiujie, O’Neill, Wendi Q., Chatfield-Reed, Kate, Yu, Jun-Ge, Teknos, Theodoros N., Pan, Quintin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978341/
https://www.ncbi.nlm.nih.gov/pubmed/31974410
http://dx.doi.org/10.1038/s41598-020-57758-5