Thermostabilization of VPR, a kinetically stable cold adapted subtilase, via multiple proline substitutions into surface loops

Protein stability is a widely studied topic, there are still aspects however that need addressing. In this paper we examined the effects of multiple proline substitutions into loop regions of the kinetically stable proteinase K-like serine protease VPR, using the thermostable structural homologue AQ...

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Detalles Bibliográficos
Autores principales: Óskarsson, K. R., Sævarsson, A. F., Kristjánsson, M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978356/
https://www.ncbi.nlm.nih.gov/pubmed/31974391
http://dx.doi.org/10.1038/s41598-020-57873-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978356/
https://www.ncbi.nlm.nih.gov/pubmed/31974391
http://dx.doi.org/10.1038/s41598-020-57873-3

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