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Differential Expression of PDGF Receptor-α in Human Placental Trophoblasts Leads to Different Entry Pathways by Human Cytomegalovirus Strains

Human cytomegalovirus (CMV) is the leading non-genetic cause of fetal malformation in developed countries. CMV placental infection is a pre-requisite for materno-fetal transmission of virus, and fetal infection. We investigated the roles of the viral pentameric complex gH/gL/pUL128-pUL131A, and cell...

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Detalles Bibliográficos
Autores principales: Naing, Zin, Hamilton, Stuart T., van Zuylen, Wendy J., Scott, Gillian M., Rawlinson, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978357/
https://www.ncbi.nlm.nih.gov/pubmed/31974453
http://dx.doi.org/10.1038/s41598-020-57471-3