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A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening
Accurate quantification of drug effects is crucial for identifying pharmaceutically actionable cancer vulnerabilities. Current cell viability-based measurements often lead to biased response estimates due to varying growth rates and experimental artifacts that explain part of the inconsistency in hi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978361/ https://www.ncbi.nlm.nih.gov/pubmed/31974521 http://dx.doi.org/10.1038/s42003-020-0765-z |