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Small stepping motion of processive dynein revealed by load-free high-speed single-particle tracking

Cytoplasmic dynein is a dimeric motor protein which processively moves along microtubule. Its motor domain (head) hydrolyzes ATP and induces conformational changes of linker, stalk, and microtubule binding domain (MTBD) to trigger stepping motion. Here we applied scattering imaging of gold nanoparti...

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Detalles Bibliográficos
Autores principales: Ando, Jun, Shima, Tomohiro, Kanazawa, Riko, Shimo-Kon, Rieko, Nakamura, Akihiko, Yamamoto, Mayuko, Kon, Takahide, Iino, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978368/
https://www.ncbi.nlm.nih.gov/pubmed/31974448
http://dx.doi.org/10.1038/s41598-020-58070-y