Cargando…

Special vulnerability of somatic niche cells to transposable element activation in Drosophila larval ovaries

In the Drosophila ovary, somatic escort cells (ECs) form a niche that promotes differentiation of germline stem cell (GSC) progeny. The piRNA (Piwi-interacting RNA) pathway, which represses transposable elements (TEs), is required in ECs to prevent the accumulation of undifferentiated germ cells (ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Sokolova, Olesya A., Mikhaleva, Elena A., Kharitonov, Sergey L., Abramov, Yuri A., Gvozdev, Vladimir A., Klenov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978372/
https://www.ncbi.nlm.nih.gov/pubmed/31974416
http://dx.doi.org/10.1038/s41598-020-57901-2