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Transcription reinitiation by recycling RNA polymerase that diffuses on DNA after releasing terminated RNA

Despite extensive studies on transcription mechanisms, it is unknown how termination complexes are disassembled, especially in what order the essential components dissociate. Our single-molecule fluorescence study unveils that RNA transcript release precedes RNA polymerase (RNAP) dissociation from t...

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Detalles Bibliográficos
Autores principales: Kang, Wooyoung, Ha, Kook Sun, Uhm, Heesoo, Park, Kyuhyong, Lee, Ja Yil, Hohng, Sungchul, Kang, Changwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978380/
https://www.ncbi.nlm.nih.gov/pubmed/31974350
http://dx.doi.org/10.1038/s41467-019-14200-3