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Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4(+) T cells

In immune-mediated hepatitis, type 2 innate lymphoid cells (ILC2) as well as effector CD4(+) T cells have been shown to drive disease pathology. However, less is known about mechanisms involved in the regulation of ILC2 function during liver inflammation. We showed that in homeostasis, hepatic ILC2...

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Detalles Bibliográficos
Autores principales: Steinmann, Silja, Schoedsack, Marek, Heinrich, Fabian, Breda, Philippe C., Ochel, Aaron, Tiegs, Gisa, Neumann, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978388/
https://www.ncbi.nlm.nih.gov/pubmed/31974518
http://dx.doi.org/10.1038/s41598-020-57985-w