Cargando…

DDAH1 promoter ‐396 4N insertion variant is associated with increased risk of type 2 diabetes in a gender‐dependent manner

BACKGROUND: Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases, making it a contributing factor for diabetes. Endogenous ADMA is hydrolyzed by dimethylarginine dimethylaminohydrolase 1 (DDAH1), and a DDAH1 promoter ‐396 4N deletion/insertion polymorphism (DDAH1...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Fasheng, Zhou, Chi, Wen, Zheng, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978400/
https://www.ncbi.nlm.nih.gov/pubmed/31733101
http://dx.doi.org/10.1002/mgg3.1011