Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome

In this study, we investigated in an androgenized rat model the involvement of autophagy and mitochondrial dynamics in granulosa cells in the pathogenesis of polycystic ovarian syndrome (PCOS) and its modulation by exogenous gonadotropin (eCG). We found 5α-dihydrotestosterone (DHT) treatment reduces...

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Detalles Bibliográficos
Autores principales: Salehi, Reza, Mazier, Hannah L., Nivet, Anne-Laure, Reunov, Arkadiy A., Lima, Patricia, Wang, Qi, Fiocco, Arianna, Isidoro, Ciro, Tsang, Benjamin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978404/
https://www.ncbi.nlm.nih.gov/pubmed/31974436
http://dx.doi.org/10.1038/s41598-020-57672-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978404/
https://www.ncbi.nlm.nih.gov/pubmed/31974436
http://dx.doi.org/10.1038/s41598-020-57672-w

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