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Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome
In this study, we investigated in an androgenized rat model the involvement of autophagy and mitochondrial dynamics in granulosa cells in the pathogenesis of polycystic ovarian syndrome (PCOS) and its modulation by exogenous gonadotropin (eCG). We found 5α-dihydrotestosterone (DHT) treatment reduces...
Autores principales: | Salehi, Reza, Mazier, Hannah L., Nivet, Anne-Laure, Reunov, Arkadiy A., Lima, Patricia, Wang, Qi, Fiocco, Arianna, Isidoro, Ciro, Tsang, Benjamin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978404/ https://www.ncbi.nlm.nih.gov/pubmed/31974436 http://dx.doi.org/10.1038/s41598-020-57672-w |
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