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Fusion of the Cas9 endonuclease and the VirD2 relaxase facilitates homology-directed repair for precise genome engineering in rice

Precise genome editing by systems such as clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) requires high-efficiency homology-directed repair (HDR). Different technologies have been developed to improve HDR but with limited success. Here, we genera...

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Detalles Bibliográficos
Autores principales: Ali, Zahir, Shami, Ashwag, Sedeek, Khalid, Kamel, Radwa, Alhabsi, Abdulrahman, Tehseen, Muhammad, Hassan, Norhan, Butt, Haroon, Kababji, Ahad, Hamdan, Samir M., Mahfouz, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978410/
https://www.ncbi.nlm.nih.gov/pubmed/31974493
http://dx.doi.org/10.1038/s42003-020-0768-9