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Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors

The number of patients diagnosed with chronic bile duct disease is increasing and in most cases these diseases result in chronic ductular scarring, necessitating liver transplantation. The formation of ductular scaring affects liver function; however, scar-generating portal fibroblasts also provide...

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Detalles Bibliográficos
Autores principales: Wilson, D. H., Jarman, E. J., Mellin, R. P., Wilson, M. L., Waddell, S. H., Tsokkou, P., Younger, N. T., Raven, A., Bhalla, S. R., Noll, A. T. R., Olde Damink, S. W., Schaap, F. G., Chen, P., Bates, D. O., Banales, J. M., Dean, C. H., Henderson, D. J., Sansom, O. J., Kendall, T. J., Boulter, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978415/
https://www.ncbi.nlm.nih.gov/pubmed/31974352
http://dx.doi.org/10.1038/s41467-020-14283-3