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Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors
The number of patients diagnosed with chronic bile duct disease is increasing and in most cases these diseases result in chronic ductular scarring, necessitating liver transplantation. The formation of ductular scaring affects liver function; however, scar-generating portal fibroblasts also provide...
Autores principales: | Wilson, D. H., Jarman, E. J., Mellin, R. P., Wilson, M. L., Waddell, S. H., Tsokkou, P., Younger, N. T., Raven, A., Bhalla, S. R., Noll, A. T. R., Olde Damink, S. W., Schaap, F. G., Chen, P., Bates, D. O., Banales, J. M., Dean, C. H., Henderson, D. J., Sansom, O. J., Kendall, T. J., Boulter, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978415/ https://www.ncbi.nlm.nih.gov/pubmed/31974352 http://dx.doi.org/10.1038/s41467-020-14283-3 |
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