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A lysosomal K(+) channel regulates large particle phagocytosis by facilitating lysosome Ca(2+) release
Macrophages are highly specialized in removing large particles including dead cells and cellular debris. When stimulated, delivery of the intracellular lysosomal membranes is required for the formation of plasmalemmal pseudopods and phagosomes. As a key lysosomal Ca(2+) channel, Transient Receptor P...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978423/ https://www.ncbi.nlm.nih.gov/pubmed/31974459 http://dx.doi.org/10.1038/s41598-020-57874-2 |