Cargando…

B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression

Tumor angiogenesis is a hallmark of cancer and is involved in the tumorigenesis of solid tumors. B7-H3, an immune checkpoint molecule, plays critical roles in proliferation, metastasis and tumorigenesis in diverse tumors; however, little is known about the biological functions and molecular mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ruoqin, Ma, Yanchao, Zhan, Shenghua, Zhang, Guangbo, Cao, Lei, Zhang, Xueguang, Shi, Tongguo, Chen, Weichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978425/
https://www.ncbi.nlm.nih.gov/pubmed/31974361
http://dx.doi.org/10.1038/s41419-020-2252-3