Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers

Controlled infection with intestinal nematodes has therapeutic potential for preventing the symptoms of allergic and autoimmune diseases. Here, we engineered larvae of the filarial nematode Litomosoides sigmodontis as a vaccine strategy to induce adaptive immunity against a foreign, crosslinked prot...

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Detalles Bibliográficos
Autores principales: Card, Catherine, Wilson, David S., Hirosue, Sachiko, Rincon-Restrepo, Marcela, de Titta, Alexandre, Güç, Esra, Martin, Coralie, Bain, Odile, Swartz, Melody A., Kilarski, Witold W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978462/
https://www.ncbi.nlm.nih.gov/pubmed/31974398
http://dx.doi.org/10.1038/s41598-020-57995-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978462/
https://www.ncbi.nlm.nih.gov/pubmed/31974398
http://dx.doi.org/10.1038/s41598-020-57995-8

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