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Improved antibody-guided surgery with a near-infrared dye on a PEGylated linker for CEA-positive tumors

Real-time intraoperative image-guided cancer surgery promises to improve oncologic outcomes. Tumor-specific antibodies conjugated with near-infrared (NIR) fluorophores have demonstrated the potential to enhance visualization of solid tumor margins and metastatic disease; however, multiple challenges...

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Detalles Bibliográficos
Autores principales: Yazaki, Paul J., Lwin, Thinzar M., Minnix, Megan, Li, Lin, Sherman, Anakim, Molnar, Justin, Miller, Aaron, Frankel, Paul, Chea, Junie, Poku, Erasmus, Bowles, Nicole, Hoffman, Robert M., Shively, John E., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978469/
https://www.ncbi.nlm.nih.gov/pubmed/31254333
http://dx.doi.org/10.1117/1.JBO.24.6.066012