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Improved antibody-guided surgery with a near-infrared dye on a PEGylated linker for CEA-positive tumors
Real-time intraoperative image-guided cancer surgery promises to improve oncologic outcomes. Tumor-specific antibodies conjugated with near-infrared (NIR) fluorophores have demonstrated the potential to enhance visualization of solid tumor margins and metastatic disease; however, multiple challenges...
Autores principales: | Yazaki, Paul J., Lwin, Thinzar M., Minnix, Megan, Li, Lin, Sherman, Anakim, Molnar, Justin, Miller, Aaron, Frankel, Paul, Chea, Junie, Poku, Erasmus, Bowles, Nicole, Hoffman, Robert M., Shively, John E., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Photo-Optical Instrumentation Engineers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978469/ https://www.ncbi.nlm.nih.gov/pubmed/31254333 http://dx.doi.org/10.1117/1.JBO.24.6.066012 |
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