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Altered dorsal CA1 neuronal population coding in the APP/PS1 mouse model of Alzheimer’s disease

While the link between amyloid β (Aβ) accumulation and synaptic degradation in Alzheimer’s disease (AD) is known, the consequences of this pathology on population coding remain unknown. We found that the entropy, a measure of the diversity of network firing patterns, was lower in the dorsal CA1 regi...

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Detalles Bibliográficos
Autores principales: Chockanathan, Udaysankar, Warner, Emily J., Turpin, Loel, O’Banion, M. Kerry, Padmanabhan, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978514/
https://www.ncbi.nlm.nih.gov/pubmed/31974405
http://dx.doi.org/10.1038/s41598-020-58038-y