Cargando…

Altered dorsal CA1 neuronal population coding in the APP/PS1 mouse model of Alzheimer’s disease

While the link between amyloid β (Aβ) accumulation and synaptic degradation in Alzheimer’s disease (AD) is known, the consequences of this pathology on population coding remain unknown. We found that the entropy, a measure of the diversity of network firing patterns, was lower in the dorsal CA1 regi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chockanathan, Udaysankar, Warner, Emily J., Turpin, Loel, O’Banion, M. Kerry, Padmanabhan, Krishnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978514/ https://www.ncbi.nlm.nih.gov/pubmed/31974405 http://dx.doi.org/10.1038/s41598-020-58038-y

Ejemplares similares

Divergence in Population Coding for Space between Dorsal and Ventral CA1
por: Chockanathan, Udaysankar, et al.
Publicado: (2021)

Gas6 induces inflammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer’s disease
por: Owlett, Laura D., et al.
Publicado: (2022)

Correction: Gas6 induces infammation and reduces plaque burden but worsens behavior in a sex-dependent manner in the APP/PS1 model of Alzheimer’s disease
por: Owlett, Laura D., et al.
Publicado: (2023)

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
por: Shaftel, Solomon S, et al.
Publicado: (2008)

Inconsistent Effects of Glatiramer Acetate Treatment in the 5xFAD Mouse Model of Alzheimer’s Disease
por: Karaahmet, Berke, et al.
Publicado: (2023)

Exploiting microglial and peripheral immune cell crosstalk to treat Alzheimer’s disease
por: Dionisio-Santos, Dawling A., et al.
Publicado: (2019)

Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation
por: Cherry, Jonathan D., et al.
Publicado: (2015)

Evaluating the Effect of Interleukin-4 in the 3xTg Mouse Model of Alzheimer’s Disease
por: Dionisio-Santos, Dawling A., et al.
Publicado: (2020)

Cognitively supernormal older adults maintain a unique structural connectome that is resistant to Alzheimer’s pathology
por: Chen, Quanjing, et al.
Publicado: (2020)

AAV gene therapy vectors in the TMJ
por: Brouxhon, Sabine M., et al.
Publicado: (2022)

Does an old dog need new tricks? Advancement of limb salvage in treating chronic limb threatening ischemia
por: O'Banion, Leigh Ann
Publicado: (2023)

Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice
por: Day, Stephen M., et al.
Publicado: (2023)

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed
por: Cherry, Jonathan D, et al.
Publicado: (2014)

Are “Resting” Microglia More “M2”?
por: Cherry, Jonathan D., et al.
Publicado: (2014)

Hyper BOLD Activation in Dorsal Raphe Nucleus of APP/PS1 Alzheimer’s Disease Mouse during Reward-Oriented Drinking Test under Thirsty Conditions
por: Sakurai, Keisuke, et al.
Publicado: (2020)

Calcitonin gene‐related peptide: An intra‐articular therapeutic target for TMJ disorders
por: Brouxhon, Sabine M., et al.
Publicado: (2022)

S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice
por: Hooijmans, Carlijn R., et al.
Publicado: (2009)

Deficits in N-Methyl-D-Aspartate Receptor Function and Synaptic Plasticity in Hippocampal CA1 in APP/PS1 Mouse Model of Alzheimer’s Disease
por: Xu, Le, et al.
Publicado: (2021)

Galactic Cosmic Radiation Leads to Cognitive Impairment and Increased Aβ Plaque Accumulation in a Mouse Model of Alzheimer’s Disease
por: Cherry, Jonathan D., et al.
Publicado: (2012)

Expression of ErbB4 in the neurons of Alzheimer's disease brain and APP/PS1 mice, a model of Alzheimer's disease
por: Woo, Ran-Sook, et al.
Publicado: (2011)

Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice
por: Kyrkanides, Stephanos, et al.
Publicado: (2011)

Brain radiation injury leads to a dose- and time-dependent recruitment of peripheral myeloid cells that depends on CCR2 signaling
por: Moravan, Michael J., et al.
Publicado: (2016)

Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathology
por: Karaahmet, Berke, et al.
Publicado: (2022)

Evaluating Effects of Glatiramer Acetate Treatment on Amyloid Deposition and Tau Phosphorylation in the 3xTg Mouse Model of Alzheimer’s Disease
por: Dionisio-Santos, Dawling A., et al.
Publicado: (2021)

Vaccine Development to Treat Alzheimer's Disease Neuropathology in APP/PS1 Transgenic Mice
por: Carrera, Iván, et al.
Publicado: (2012)

NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice
por: Heneka, Michael T., et al.
Publicado: (2012)

Conditional expression of human β-hexosaminidase in the neurons of Sandhoff disease rescues mice from neurodegeneration but not neuroinflammation
por: Kyrkanides, Stephanos, et al.
Publicado: (2012)

Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer’s disease mice
por: Jew, Katrina, et al.
Publicado: (2019)

EGCG and nimodipine improve the symptoms of AD by inhibiting [Ca2+]i in hippocampal neurons of APP/PS1 transgenic mice
por: Wang, Shuang, et al.
Publicado: (2012)

Vitis vinifera L. Flavones Regulate Hippocampal Neurons via Autophagy in APP/PS1 Alzheimer Model Mice
por: Zhang, Peng, et al.
Publicado: (2022)

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice
por: Hiltunen, Mikko, et al.
Publicado: (2012)

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease
por: Webster, Scott J, et al.
Publicado: (2013)

Isolation Housing Exacerbates Alzheimer’s Disease-Like Pathophysiology in Aged APP/PS1 Mice
por: Huang, Huang, et al.
Publicado: (2015)

PT573. The effects of intestinal endotoxemia on APP, PS1 and BACE expression in Alzheimer’s disease
por: Han, Bai, et al.
Publicado: (2016)

Untargeted lipidomics reveals progression of early Alzheimer’s disease in APP/PS1 transgenic mice
por: Zhang, Xueju, et al.
Publicado: (2020)

Milrinone Ameliorates the Neuroinflammation and Memory Function of Alzheimer’s Disease in an APP/PS1 Mouse Model
por: Chen, Qingyou, et al.
Publicado: (2021)

Effects of multi-mode physical stimulation on APP/PS1 Alzheimer's disease model mice
por: Liu, Shupeng, et al.
Publicado: (2022)

Neuroprotective effects of resistance physical exercise on the APP/PS1 mouse model of Alzheimer’s disease
por: Campos, Henrique Correia, et al.
Publicado: (2023)

IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia
por: Rivera-Escalera, Fátima, et al.
Publicado: (2019)

Surgical management of a large mycotic aneurysm of the distal popliteal artery
por: McCullough, Kyle, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cjske0i5b0rs8c33d6cjogopn5