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Telomeres as Therapeutic Targets in Heart Disease

Telomeres are double-stranded repeats of G-rich tandem DNA sequences that gradually shorten with each cell division. Aging, inflammation, and oxidative stress accelerate the process of telomere shortening. Telomerase counteracts this process by maintaining and elongating the telomere length. Patient...

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Detalles Bibliográficos
Autores principales: Yeh, Jih-Kai, Lin, Mei-Hsiu, Wang, Chao-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978555/
https://www.ncbi.nlm.nih.gov/pubmed/31998853
http://dx.doi.org/10.1016/j.jacbts.2019.05.009