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Toxicity evaluation and nasal mucosal tissue deposition of dexamethasone-infused mucoadhesive in situ nasal gelling systems

To demonstrate safety of a developed intranasal dexamethasone-infused in situ gelling formulation, quantification of a validated clinical biomarker indicative of cytotoxic potential using a human sinonasal explant model was first confirmed. Systematic cytotoxicity studies using the lactate dehydroge...

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Detalles Bibliográficos
Autores principales: Pandey, Preeti, Pandey, Saurabh, Cabot, Peter J., Wallwork, Benjamin, Panizza, Benedict J., Parekh, Harendra S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978612/
https://www.ncbi.nlm.nih.gov/pubmed/31997897
http://dx.doi.org/10.1016/j.jsps.2019.06.005