Synthesis, biological evaluations and molecular modelling studies of novel indolin-2-ones designing as FGFR inhibitors

A series of novel 3,5-disubstituted indolin-2-ones were designed and synthesized as selective FGFR inhibitors. In the design process of 3,5-disubstituted indolin-2-ones for FGFRs, molecular docking studies were performed to generate and optimize novel compounds which have FGFR inhibitory potency, th...

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Detalles Bibliográficos
Autores principales: Çoban, Güneş, Aydın Köse, Fadime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978637/
https://www.ncbi.nlm.nih.gov/pubmed/31997902
http://dx.doi.org/10.1016/j.jsps.2019.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978637/
https://www.ncbi.nlm.nih.gov/pubmed/31997902
http://dx.doi.org/10.1016/j.jsps.2019.07.004

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