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Synthesis, biological evaluations and molecular modelling studies of novel indolin-2-ones designing as FGFR inhibitors
A series of novel 3,5-disubstituted indolin-2-ones were designed and synthesized as selective FGFR inhibitors. In the design process of 3,5-disubstituted indolin-2-ones for FGFRs, molecular docking studies were performed to generate and optimize novel compounds which have FGFR inhibitory potency, th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978637/ https://www.ncbi.nlm.nih.gov/pubmed/31997902 http://dx.doi.org/10.1016/j.jsps.2019.07.004 |