Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations

Bupropion, a Food and Drug Administration–approved antidepressant and smoking cessation aid, blocks dopamine and norepinephrine reuptake transporters and noncompetitively inhibits nicotinic acetylcholine and serotonin (5-HT) type 3A receptors (5-HT(3A)Rs). 5-HT(3) receptors are pentameric ligand-gat...

Descripción completa

Detalles Bibliográficos
Autores principales: Stuebler, Antonia G., Jansen, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978693/
https://www.ncbi.nlm.nih.gov/pubmed/31871303
http://dx.doi.org/10.1124/mol.119.118349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978693/
https://www.ncbi.nlm.nih.gov/pubmed/31871303
http://dx.doi.org/10.1124/mol.119.118349

Ejemplares similares