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Bupropion Inhibits Serotonin Type 3AB Heteromeric Channels at Clinically Relevant Concentrations

Bupropion, a Food and Drug Administration–approved antidepressant and smoking cessation aid, blocks dopamine and norepinephrine reuptake transporters and noncompetitively inhibits nicotinic acetylcholine and serotonin (5-HT) type 3A receptors (5-HT(3A)Rs). 5-HT(3) receptors are pentameric ligand-gat...

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Detalles Bibliográficos
Autores principales:	Stuebler, Antonia G., Jansen, Michaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978693/ https://www.ncbi.nlm.nih.gov/pubmed/31871303 http://dx.doi.org/10.1124/mol.119.118349

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