Protective Allele for Multiple Sclerosis HLA-DRB1*01:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides

Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may have a protective effect. Here we analyzed distribution of a highly polymorphous HLA-DRB1 locus in more than one thous...

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Detalles Bibliográficos
Autores principales: Mamedov, Azad, Vorobyeva, Nadezhda, Filimonova, Ioanna, Zakharova, Maria, Kiselev, Ivan, Bashinskaya, Vitalina, Baulina, Natalia, Boyko, Alexey, Favorov, Alexander, Kulakova, Olga, Ziganshin, Rustam, Smirnov, Ivan, Poroshina, Alina, Shilovskiy, Igor, Khaitov, Musa, Sykulev, Yuri, Favorova, Olga, Vlassov, Valentin, Gabibov, Alexander, Belogurov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978714/
https://www.ncbi.nlm.nih.gov/pubmed/32010139
http://dx.doi.org/10.3389/fimmu.2019.03088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978714/
https://www.ncbi.nlm.nih.gov/pubmed/32010139
http://dx.doi.org/10.3389/fimmu.2019.03088

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