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Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons
Teneurins are ancient metazoan cell adhesion receptors that control brain development and neuronal wiring in higher animals. The extracellular C terminus binds the adhesion GPCR Latrophilin, forming a trans-cellular complex with synaptogenic functions. However, Teneurins, Latrophilins, and FLRT prot...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978801/ https://www.ncbi.nlm.nih.gov/pubmed/31928845 http://dx.doi.org/10.1016/j.cell.2019.12.014 |