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DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites

[Image: see text] Malaria is the deadliest parasitic disease affecting over 200 million people worldwide. The increasing number of treatment failures due to multi-drug-resistant parasites in South-East Asia hinders the efforts for elimination. It is thus urgent to develop new antimalarials to contai...

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Detalles Bibliográficos
Autores principales: Nardella, Flore, Halby, Ludovic, Hammam, Elie, Erdmann, Diane, Cadet-Daniel, Véronique, Peronet, Roger, Ménard, Didier, Witkowski, Benoit, Mecheri, Salah, Scherf, Artur, Arimondo, Paola B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978834/
https://www.ncbi.nlm.nih.gov/pubmed/31989022
http://dx.doi.org/10.1021/acscentsci.9b00874