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An Activity-Based Methionine Bioconjugation Approach To Developing Proximity-Activated Imaging Reporters

[Image: see text] Chemical probes that report on protein activity, rather than protein abundance, with spatial and temporal resolution can enable studies of their native function in biological contexts as well as provide opportunities for developing new types of biochemical reporters. Here we presen...

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Detalles Bibliográficos
Autores principales: Ohata, Jun, Krishnamoorthy, Lakshmi, Gonzalez, Monica A., Xiao, Tong, Iovan, Diana A., Toste, F. Dean, Miller, Evan W., Chang, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978837/
https://www.ncbi.nlm.nih.gov/pubmed/31989024
http://dx.doi.org/10.1021/acscentsci.9b01038