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Naturally Occurring Sclareol Diterpene Augments the Chemosensitivity of Human Hela Cervical Cancer Cells by Inducing Mitochondrial Mediated Programmed Cell Death, S-Phase Cell Cycle Arrest and Targeting Mitogen-Activated Protein Kinase (MAPK)/Extracellular-Signal-Regulated Kinase (ERK) Signaling Pathway

BACKGROUND: Cervical cancer is a major threat to female health worldwide. This study was performed to study the anticancer potential of sclareol and as a chemo-sensitizing agent against human cervical cancer cells along with evaluating its effects on apoptosis, cell cycle arrest, and MAPK/ERK signal...

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Detalles Bibliográficos
Autores principales: Li, Wang, Ping, Zhou, Xuemei, Gao, Minglian, Luo, Hongjuan, Meng, Yi, He, Zhongxiang, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6978991/
https://www.ncbi.nlm.nih.gov/pubmed/31935210
http://dx.doi.org/10.12659/MSM.920248