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Identification of potential drugs for treatment of hepatic lipidosis in cats using an in vitro feline liver organoid system

BACKGROUND: Hepatic lipidosis is increasing in incidence in the Western world, with cats being particularly sensitive. When cats stop eating and start utilizing their fat reserves, free fatty acids (FFAs) increase in blood, causing an accumulation of triacylglycerol (TAG) in the liver. OBJECTIVE: Id...

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Detalles Bibliográficos
Autores principales: Haaker, Maya W., Kruitwagen, Hedwig S., Vaandrager, Arie B., Houweling, Martin, Penning, Louis C., Molenaar, Martijn R., van Wolferen, Monique E., Oosterhoff, Loes A., Spee, Bart, Helms, J. Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979087/
https://www.ncbi.nlm.nih.gov/pubmed/31830357
http://dx.doi.org/10.1111/jvim.15670