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Mycobacterial virulence: impact on immunogenicity and vaccine research

The borderline between virulence and efficacy in live attenuated vaccine strains is often blurred and this is also the case for the Bacillus Calmette–Guérin (BCG), the only currently licensed anti-tuberculosis vaccine used on a large, global scale, which was obtained almost 100 years ago. While BCG...

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Detalles Bibliográficos
Autores principales: Kroesen, Vera M., Madacki, Jan, Frigui, Wafa, Sayes, Fadel, Brosch, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979476/
https://www.ncbi.nlm.nih.gov/pubmed/32047597
http://dx.doi.org/10.12688/f1000research.20572.1