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Genome-wide CRISPR screening identifies new regulators of glycoprotein secretion

Background: The fundamental process of protein secretion from eukaryotic cells has been well described for many years, yet gaps in our understanding of how this process is regulated remain. Methods: With the aim of identifying novel genes involved in the secretion of glycoproteins, we used a screeni...

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Detalles Bibliográficos
Autores principales: Popa, Stephanie, Villeneuve, Julien, Stewart, Sarah, Perez Garcia, Esther, Petrunkina Harrison, Anna, Moreau, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979480/
https://www.ncbi.nlm.nih.gov/pubmed/32030357
http://dx.doi.org/10.12688/wellcomeopenres.15232.2