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Population genetic simulation study of power in association testing across genetic architectures and study designs

While it is well established that genetics can be a major contributor to population variation of complex traits, the relative contributions of rare and common variants to phenotypic variation remains a matter of considerable debate. Here, we simulate genetic and phenotypic data across different case...

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Detalles Bibliográficos
Autores principales: Tong, Dominic M. H., Hernandez, Ryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980249/
https://www.ncbi.nlm.nih.gov/pubmed/31587362
http://dx.doi.org/10.1002/gepi.22264