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Population genetic simulation study of power in association testing across genetic architectures and study designs
While it is well established that genetics can be a major contributor to population variation of complex traits, the relative contributions of rare and common variants to phenotypic variation remains a matter of considerable debate. Here, we simulate genetic and phenotypic data across different case...
Autores principales: | Tong, Dominic M. H., Hernandez, Ryan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980249/ https://www.ncbi.nlm.nih.gov/pubmed/31587362 http://dx.doi.org/10.1002/gepi.22264 |
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